http://www.alternative-medicine-naturopathy.com Cell-therapy: Stem cell transplant is not a “wonder drug”, or a transplant of some “wonder cell” that will cure everything. A study by Georg v. Falkenhayn n.M.D. 23.10.2006 09:10 http://www.alternative-medicine-naturopathy.com/stem-cell-transplant.html Stem Cell Transplant Case Study Georg v. Falkenhayn N.M.D. Doctor of Naturopathic Medicine (Southern College of Naturopathic Physicians, Fayetteville, N.C. / The USA) (Stem) Cell Transplant (SCT) is a surgical procedure that has been developed during the last 120+ years and used successfully for 75+ years as treatment of many diseases for which modern medicine has had no therapy, or in which 'state-of-art' therapies stopped being effective. A documented ~ 5 millions of patients have been so treated worldwide to-date. Stem cell transplant is not a “wonder drug”, or a transplant of some “wonder cell” that will cure everything. The body of every member of the animal kingdom, including man, is built from about 200 kinds of cells, and since 1998 Bio-Cellular Research Organization (“BCRO”) has been manufacturing stem cell transplants of every known kind of cell and made such transplants available for the treatment, without immunosuppression. It has been a result of our 25+ years' of research, GMP (‘good manufacturing practice’), and clinical experience with stem cell transplant in thousands of patients suffering from those diseases where physicians recognized that their patient needs an outright transplant of fetal cells to replace the dead or non-functioning cells, or a direct stimulation of regeneration (i.e. repair) of the damaged cells and tissues of various organs. Among such diseases are: 1- Diabetes Mellitus, types 1 and mixed 1/2, particularly when complications have already developed, such as: - Diabetic Retinopathy - Diabetic Nephropathy - Diabetic Polyneuropathy - Diabetic Lower Extremity Arterial Disease, as well as Brittle Diabetes Mellitus in children, and Diabetes Mellitus in pregnancy, or diabetes mellitus as a cause of female infertility and habitual pregnancy loss. 2- Other hormone deficiency disorders, where hormone replacement therapy could not re-establish a normal hormonal balance; 3- Early Menopause, and some other serious gynecological diseases, where state-of-art treatment has failed; 4- Male and female infertility, where usual treatment has failed; 5- Immune deficiency disorders, such as chronic weakness syndrome, AIDS, cancer, etc., as well as autoimmune illnesses; 6- Aging disease, including menopause, impotence, depression, etc. 7- Parkinson’s and other degenerative diseases of the central nervous system; 8- Degenerative diseases of liver, gastrointestinal tract, cardiovascular system, and other organ systems; 9- Many genetic and chromosomal diseases of children, such as Down syndrome, as well as failure to thrive, mental retardation, frequent illnesses, etc., due to various prenatal, natal or postnatal causes. 10- Any & all diseases where the direct stimulation of regeneration is considered of major importance for the treatment of a disease(s) of a specific patient. There are many published medical reports on hundreds of patients showing that changes of laboratory parameters of the immune system function before and after stem cell transplant are minimal and statistically not significant. Long-term immunosuppression is not only dangerous to the patients, it is detrimental to stem cell transplants, because these are very young cells, enormously sensitive to any toxin, such as immunosuppressants. Many medical research and clinical reports, nearly all in German, Russian, and other languages, including that of BCRO, contain groundbreaking data on which the entire field of stem cell transplant has been based. Besides five million patients treated, mostly in Germany, of which ~1 million have been treated with ‘stem cell containing fresh cell transplants’, an estimated 20 million patients worldwide received in the U.S.S.R. developed live human placental tissue implantations with trophoblastic cells. Germany and U.S.S.R. have been the leaders in stem cell transplant for the past 75 years. Stem cell transplant was introduced into clinical practice in 1931 and has historically preceded organ transplant by several decades. It will dominate the medicine of 21st century because 1- Stem cell transplant is a minor procedure for a patient, and for that reason should be used in the earlier stages of those diseases that current medicine cannot cure, or even treat. There is no logical reason to wait until the end-stage, as is the case with organ transplant, and has been the case with (stem) cell transplant until now. 2- One of the reasons why stem cell transplant is such a simple procedure for a patient is the principle of “homing”. “Homing” means that the respective stem cells do not have to be implanted into a damaged organ, (e.g. liver stem cells into liver), they can be implanted into more accessible superficial tissues, (e.g. under the aponeurosis of an abdominal muscle), because they will find their way into the damaged organ, as if ‘attracted’ by it. 3- Every diseased organ can be treated by stem cell transplant but not by organ transplant. Besides serving as a replacement for dead cells of a diseased organ, the transplanted cells can bring back to life (or repair) those cells of such organ which actually have not died, just stopped functioning. In other words, besides transplanting new stem cells there is another mechanism of action of stem cell transplant: ‘direct stimulation of regeneration (or repair)’. 4- If stem cells are properly prepared, such as by BCRO method, they can be implanted without immunosuppression, and thus avoid all complications caused by the use of such medications. Stem cell transplants can be manufactured for clinical use from fetuses of any member of the animal kingdom, from Homo Sapiens to fish. The frontal lobe of the brain is the sole body part unique to man, and absent in all animals. All other stem cell transplants can be obtained from animal sources. Why stem cell transplants of animal fetal origin can be used instead of those human origin. 1- It has been known since 19th century, and the entire modern cell biology is based on the fact, that all eukaryotic cells in Nature are built and function according to the same laws. In clinical practice of stem cell transplant only eukaryotic cells have been used. 2- Main cells of the same organ or tissue are the same in Nature, (or nearly the same), regardless of the species of origin. Corresponding cells of the identical organ of different animal species (including man) are biologically similar. Scientists call this a "principle of organospecificity". There are no antigenic differences between the corresponding cells of the identical organ of different animal species (including man): another proof of "organospecificity". 3- All biological systems in Nature are composed of the same types of molecules: it is known as a "principle of homology". 4- The basic law of molecular biology, whereby DNA directs the synthesis of RNA, which in turn directs the assembly of proteins, applies to all living beings. Genetic encoding is the same in most known organisms. BCRO has always manufactured stem cell transplants from rabbit fetuses (with the exception of stem cell transplants of various endocrine glands, where newborn rabbits have been the animal source). According to the world’s medical literature (and confirmed by the World Health Organization), no transmission of any viral disease has been known to occur from rabbit to man. Rabbits are the sole laboratory animal in which no retroviruses have been identified yet, despite the fact that they should be present in all mammals. No genetic manipulations are used in the preparation of stem cell transplants by BCRO method. Schönberg, June 2006 Contentwise responsibility and to the establishment of contact: Georg v. Falkenhayn n.M.D. Bahnhofstraße 13a 24217 Schoenberg - Germany Fon: 0049 - 4344 - 301 740 Fax: 0049 - 4344 - 301 741 see: Clinic-web-site E-mail: info@von-falkenhayn.com for further information visit my website 23.10.2006 8:56